Endocrine Abstracts

The aim of our study was to evaluate the influence of rhTSH on the efficacy of radioiodine therapy (RIT) in patients with toxic nodular goitre(TNG) with low RAIU. Materials and methods: The study was performed on 30 patients with TNG (22 female and 8 male aged 45–78years) referred for 131I therapy. All patients had low RAIU (16–18%) 24 hours after a diagnostic dose of I-131 (4 MBq). All the patients received a single intramuscular dose of 0.05 mg rhTSH (thyrogen). 24...

The aim of our study was to evaluate the short term efficacy of radioiodine therapy (RIT) to reduce thyroid volume with minimal risk of hypothyroidism in patients with non-toxic nodular goitre. Material and Methods: We treated 120 patients, aged 20–76 years; (88%) of the studied groups were female and (12%) male. Initial 24 h RAIU was ranged between 22–44% and effective half-life was more than 3 days. Thyroid volume ranged between 42–170 ml. Malignant changes we...